Table 2

Inhibitory Effect of Crude Green Tea Extracts

on the Growth of Mouse Sarcoma 180 Tumor

 

 

Dose

 

(mg/kg/day)

Average Tumor

Weight(a)

(g)

Inhibition

Ratio

(%)

Control

Extracts

 

 

MitomycinC

-

200p.o.× 4

400p.o.× 4

800p.o.× 4

2i.p.× 4

2.04±0.82

1.85±1.34

1.02±0.20

0.82±0.55

0.37±0.20

-

9.3

50.0(b)

59.8(c)

81.9(c)

(a):The means ±S.E. (b):p>0.05 (c):p>0.01

 

The crude extacts of green tea leaves were daily administered to ICR mice orally

for 4 days after subcutaneous inoculation of sarcoma 180 cells( 1×107 cell/mouse).

Mitomycin C was used as a positive control. Tumor weight was compared with that of

the control (10 mice/group) on the 21st day after inoculation.