@
Table 3
Inhibitory Effect Green Tea Extract on the Induction of
Tumors in Mice by in vivo Formation of Nitrososarcosine
from its Precursors, Sarcosine and Sodium nitrite
@
|
@ Group |
@ Treatment |
@ No.of Mice |
Incidence of Esophageal Papilloma(%) |
Incidence of Carcinonia(%) | ||
|
Esophagus @ |
Forestomach |
Total | ||||
|
@ T @ |
Sarcosine + NaNO 2 |
@ 47 @ |
@ 33(70.2) @ |
@ 3 @ |
@ 16 |
@ 19(40.4) @ |
|
@ @ II |
GTE + Sarcosine + NaNO 2 |
@ @ 45 |
@ @ 20(44.4)(a) |
@ @ 0 @ @ |
@ @ 8 @ @ |
@ @ 8(17.8)(a) @ |
(a):p>0.05 GTE:Green Tea Extract
@
Green tea extract (5mg/mouse/day) was intubated to mice (Tientsin IIAfemale)
6 times a week, for 14 weeks. From the second week, mice of both Group I and II were
intubated with sarcosine ethyl ester hydrochloride (2g/Kg) and sodium nitrite (0.3g/Kg)
3 times a week, for total 5 weeks. The animals were sacrificed at the 14th week.