Table 8
Inhibitory effects of (-)-epicatechin gallate and (-)-epigallocatechin
Gallate on the activities of HIV-reversetranscriptase and various
DNA and RNA polymerases (IC
50 values in ug/ml)
|
DNA and RNA polymerases |
(-)-Epicatechin gallate |
(-)-Epigallocatechin gallate |
|
HIV-1 everse transcriptase |
0.017 |
|
|
DNA polymerase α |
0.13 |
|
|
DNA polymerase β |
0.12 |
|
|
DNA polymerase γ |
0.9 |
|
|
E.coli RNA polymerase |
0.25 |
0.13 |